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Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis of spatially matched molecular and multi-parametric magnetic resonance imaging (MRI) profi...

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Detalles Bibliográficos
Autores principales: Hu, Leland S., D’Angelo, Fulvio, Weiskittel, Taylor M., Caruso, Francesca P., Fortin Ensign, Shannon P., Blomquist, Mylan R., Flick, Matthew J., Wang, Lujia, Sereduk, Christopher P., Meng-Lin, Kevin, De Leon, Gustavo, Nespodzany, Ashley, Urcuyo, Javier C., Gonzales, Ashlyn C, Curtin, Lee, Lewis, Erika M., Singleton, Kyle W., Dondlinger, Timothy, Anil, Aliya, Semmineh, Natenael B., Noviello, Teresa, Patel, Reyna A., Wang, Panwen, Wang, Junwen, Eschbacher, Jennifer M., Hawkins-Daarud, Andrea, Jackson, Pamela R., Grunfeld, Itamar S., Elrod, Christian, Mazza, Gina L., McGee, Sam C., Paulson, Lisa, Clark-Swanson, Kamala, Lassiter-Morris, Yvette, Smith, Kris A., Nakaji, Peter, Bendok, Bernard R., Zimmerman, Richard S., Krishna, Chandan, Patra, Devi P., Patel, Naresh P., Lyons, Mark, Neal, Matthew, Donev, Kliment, Mrugala, Maciej M., Porter, Alyx B., Beeman, Scott C., Jensen, Todd R., Schmainda, Kathleen M., Zhou, Yuxiang, Baxter, Leslie C., Plaisier, Christopher L., Li, Jing, Li, Hu, Lasorella, Anna, Quarles, C. Chad, Swanson, Kristin R., Ceccarelli, Michele, Iavarone, Antonio, Tran, Nhan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539500/
https://www.ncbi.nlm.nih.gov/pubmed/37770427
http://dx.doi.org/10.1038/s41467-023-41559-1