Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program

BACKGROUND: Glioblastoma (GBM), one of the most lethal tumors, exhibits a highly infiltrative phenotype. Here, we identified transcription factors (TFs) that collectively modulate invasion-related genes in GBM. METHODS: The invasiveness of tumorspheres (TSs) were quantified using collagen-based 3D i...

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Detalles Bibliográficos
Autores principales: Park, Junseong, Shim, Jin-Kyoung, Lee, Mirae, Kim, Dokyeong, Yoon, Seon-Jin, Moon, Ju Hyung, Kim, Eui Hyun, Park, Jeong-Yoon, Chang, Jong Hee, Kang, Seok-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539507/
https://www.ncbi.nlm.nih.gov/pubmed/37558923
http://dx.doi.org/10.1038/s41416-023-02391-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539507/
https://www.ncbi.nlm.nih.gov/pubmed/37558923
http://dx.doi.org/10.1038/s41416-023-02391-y

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