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Circulating biomarkers of extracellular matrix dysregulation are associated with adverse post-stage 2 outcomes in infants with single ventricle heart disease

Children with single ventricle heart disease (SVHD) experience morbidity due to inadequate pulmonary blood flow. Using proteomic screening, our group previously identified members of the matrix metalloproteinase (MMP), tissue inhibitor of metalloproteinase (TIMP), and fibroblast growth factor (FGF)...

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Detalles Bibliográficos
Autores principales: Frank, Benjamin S., Nandy, Debmalya, Khailova, Ludmila, Mitchell, Max B., Morgan, Gareth J., Twite, Mark, DiMaria, Michael V., Davidson, Jesse A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539532/
https://www.ncbi.nlm.nih.gov/pubmed/37770592
http://dx.doi.org/10.1038/s41598-023-43562-4