Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Hematopoietic stem cells (HSCs) residing in specialized niches in the bone marrow are responsible for the balanced output of multiple short-lived blood cell lineages in steady-state and in response to different challenges. However, feedback mechanisms by which HSCs, through their niches, sense acute...

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Detalles Bibliográficos
Autores principales: Luis, Tiago C., Barkas, Nikolaos, Carrelha, Joana, Giustacchini, Alice, Mazzi, Stefania, Norfo, Ruggiero, Wu, Bishan, Aliouat, Affaf, Guerrero, Jose A., Rodriguez-Meira, Alba, Bouriez-Jones, Tiphaine, Macaulay, Iain C., Jasztal, Maria, Zhu, Guangheng, Ni, Heyu, Robson, Matthew J., Blakely, Randy D., Mead, Adam J., Nerlov, Claus, Ghevaert, Cedric, Jacobsen, Sten Eirik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539537/
https://www.ncbi.nlm.nih.gov/pubmed/37770432
http://dx.doi.org/10.1038/s41467-023-41691-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539537/
https://www.ncbi.nlm.nih.gov/pubmed/37770432
http://dx.doi.org/10.1038/s41467-023-41691-y

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