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Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection

Neurotoxicity of organophosphate compounds (OPs) can catastrophically cause nervous system injury by inhibiting acetylcholinesterase (AChE) expression. Although artificial systems have been developed for indirect neuroprotection, they are limited to dissociating P-O bonds for eliminating OPs. Howeve...

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Detalles Bibliográficos
Autores principales: Xu, Weiqing, Cai, Xiaoli, Wu, Yu, Wen, Yating, Su, Rina, Zhang, Yu, Huang, Yuteng, Zheng, Qihui, Hu, Liuyong, Cui, Xiaowen, Zheng, Lirong, Zhang, Shipeng, Gu, Wenling, Song, Weiyu, Guo, Shaojun, Zhu, Chengzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539540/
https://www.ncbi.nlm.nih.gov/pubmed/37770453
http://dx.doi.org/10.1038/s41467-023-41765-x