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LTe2 induces cell apoptosis in multiple myeloma by suppressing AKT phosphorylation at Thr308 and Ser473

Multiple myeloma (MM) is a highly heterogeneous hematological malignancy originating from B lymphocytes, with a high recurrence rate primarily due to drug resistance. 2-((1H-indol-3-yl)methyl)-3-((3-((1H-indol-3-yl)methyl)-1H-indol-2-yl)methyl)-1H-indole (LTe2), a tetrameric indole oligomer, possess...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanjiao, Qian, Jiacheng, Jiang, Mingmei, Yang, Shu, Zhou, Lianxin, Zhang, Qin, Lin, Liping, Yang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539572/
https://www.ncbi.nlm.nih.gov/pubmed/37781194
http://dx.doi.org/10.3389/fonc.2023.1269670