Treatment of rheumatoid arthritis with baricitinib or upadacitinib is associated with reduced scaffold protein NEDD9 levels in CD4+ T cells

The JAK/STAT pathway plays a crucial role in the pathogenesis of rheumatoid arthritis (RA) and JAK inhibitors have emerged as a new group of effective drugs for RA treatment. Recently, high STAT3 levels have been associated with the upregulation of the scaffold protein NEDD9, which is a regulator of...

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Detalles Bibliográficos
Autores principales: Golumba‐Nagy, Viktoria, Yan, Shuaifeng, Steinbach‐Knödgen, Eva, Thiele, Jan, Esser, Ruth L., Haak, Thomas H., Nikiforov, Anastasia, Meyer, Anja, Seeger‐Nukpezah, Tamina, Kofler, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539626/
https://www.ncbi.nlm.nih.gov/pubmed/37771106
http://dx.doi.org/10.14814/phy2.15829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539626/
https://www.ncbi.nlm.nih.gov/pubmed/37771106
http://dx.doi.org/10.14814/phy2.15829

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