Cargando…

TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes

TNFα-mediated signaling pathways play a pivotal role in the pathogenesis of inflammatory diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) by promoting phagocyte inflammatory functions, notably cytokine release and reactive oxygen species (ROS) production by NOX2. In co...

Descripción completa

Detalles Bibliográficos
Autores principales: Ben-Khemis, Marwa, Liu, Dan, Pintard, Coralie, Song, Zhuoyao, Hurtado-Nedelec, Margarita, Marie, Jean-Claude, El-Benna, Jamel, Dang, Pham My-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539668/
https://www.ncbi.nlm.nih.gov/pubmed/37757542
http://dx.doi.org/10.1016/j.redox.2023.102898