Tofacitinib Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglial Polarization via JAK/STAT Signaling Pathway

Background: The JAK/STAT signaling pathway is the main inflammatory signal transduction pathway, whether JAK/STAT contributes the pathology of SCI and targeting the pathway will alleviate SCI needs to be addressed. Here, we explored the therapeutic effect of pan-JAK inhibitor tofacitinib (TOF) on se...

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Detalles Bibliográficos
Autores principales: Ma, Hongdao, Wang, Chenfeng, Han, Lin, Kong, Fanqi, Liu, Zhixiao, Zhang, Bangke, Chu, Wenxiang, Wang, Haibin, Wang, Liang, Li, Qisheng, Peng, Weilin, Yang, Haisong, Han, Chaofeng, Lu, Xuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539697/
https://www.ncbi.nlm.nih.gov/pubmed/37781508
http://dx.doi.org/10.7150/ijbs.84564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539697/
https://www.ncbi.nlm.nih.gov/pubmed/37781508
http://dx.doi.org/10.7150/ijbs.84564

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