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p53 and MYC-regulated squalene epoxidase as Achilles heel in colorectal cancer
The transcription factors p53 and MYC are often considered non-druggable targets, but their dysregulation can generate new dependencies and treatment opportunities in cancer cells. The p53 and MYC-regulated squalene epoxidase (SQLE) has been identified as a potential Achilles heel in colorectal canc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Ivyspring International Publisher
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539706/ https://www.ncbi.nlm.nih.gov/pubmed/37781510 http://dx.doi.org/10.7150/ijbs.89237 |