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Precise Orchestration of Gasdermins' Pore-Forming Function by Posttranslational Modifications in Health and Disease

Gasdermins (GSDMs) serve as pivotal executors of pyroptosis and play crucial roles in host defence, cytokine secretion, innate immunity, and cancer. However, excessive or inappropriate GSDMs activation is invariably accompanied by exaggerated inflammation and results in tissue damage. In contrast, d...

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Detalles Bibliográficos
Autores principales: Jiang, Haiyang, Liu, Peizhao, Kang, Jiaqi, Wu, Jie, Gong, Wenbin, Li, Xuanheng, Li, Yangguang, Liu, Juanhan, Li, Weizhen, Ni, Chujun, Liao, Bo, Wu, Xiuwen, Zhao, Yun, Ren, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539709/
https://www.ncbi.nlm.nih.gov/pubmed/37781519
http://dx.doi.org/10.7150/ijbs.86869