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Extracellular vesicle‑mediated RNA editing may underlie the heterogeneity and spread of hepatocellular carcinoma in human tissue and in vitro

Extracellular vesicles (EVs) produced by various cells, including tumor cells, carry biomolecules to neighboring cells. In hepatocellular carcinoma (HCC), adenosine to inosine RNA editing of antizyme inhibitor 1 (AZIN1), specifically regulated by adenosine deaminase acting on RNA-1 (ADAR1), promotes...

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Detalles Bibliográficos
Autores principales: Shibata, Chikako, Otsuka, Motoyuki, Shimizu, Takayuki, Seimiya, Takahiro, Kishikawa, Takahiro, Aoki, Taku, Fujishiro, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539718/
https://www.ncbi.nlm.nih.gov/pubmed/37732519
http://dx.doi.org/10.3892/or.2023.8631