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Four-dimensional NOE-NOE spectroscopy of SARS-CoV-2 Main Protease to facilitate resonance assignment and structural analysis
Resonance assignment and structural studies of larger proteins by nuclear magnetic resonance (NMR) can be challenging when exchange broadening, multiple stable conformations, and [Formula: see text] H back-exchange of the fully deuterated chain pose problems. These difficulties arise for the SARS-Co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Copernicus GmbH
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539749/ https://www.ncbi.nlm.nih.gov/pubmed/37904772 http://dx.doi.org/10.5194/mr-2-129-2021 |