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Structural polymorphism and substrate promiscuity of a ribosome-associated molecular chaperone

Trigger factor (TF) is a highly conserved multi-domain molecular chaperone that exerts its chaperone activity at the ribosomal tunnel exit from which newly synthesized nascent chains emerge. TF also displays promiscuous substrate binding for a large number of cytosolic proteins independent of riboso...

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Detalles Bibliográficos
Autores principales: Huang, Chih-Ting, Lai, Yei-Chen, Chen, Szu-Yun, Ho, Meng-Ru, Chiang, Yun-Wei, Hsu, Shang-Te Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539794/
https://www.ncbi.nlm.nih.gov/pubmed/37904759
http://dx.doi.org/10.5194/mr-2-375-2021