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Enriching single-arm clinical trials with external controls: possibilities and pitfalls
For the past decade, it has become commonplace to provide rapid answers and early patient access to innovative treatments in the absence of randomized clinical trials (RCT), with benefits estimated from single-arm trials. This trend is important in oncology, notably when assessing new targeted thera...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539876/ https://www.ncbi.nlm.nih.gov/pubmed/36534147 http://dx.doi.org/10.1182/bloodadvances.2022009167 |