ABBV-744 induces autophagy in gastric cancer cells by regulating PI3K/AKT/mTOR/p70S6k and MAPK signaling pathways

The mortality rates of gastric cancer remain high due to limited therapeutic strategies. As a highly selective inhibitor of the BD2 domain of BET family proteins, ABBV-744 has potent chemotherapeutic activity against various human solid tumors. However, whether ABBV-744 has potential anti-tumor effe...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Tang, Jiatong, Fan, Shengxian, Su, Haochen, Yu, Ranran, Zhang, Yixuan, Wu, Hao, Lv, Ying, Zhang, Shu, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539879/
https://www.ncbi.nlm.nih.gov/pubmed/37769529
http://dx.doi.org/10.1016/j.neo.2023.100936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539879/
https://www.ncbi.nlm.nih.gov/pubmed/37769529
http://dx.doi.org/10.1016/j.neo.2023.100936

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