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Quantitative approaches for decoding the specificity of the human T cell repertoire

T cell receptor (TCR)-peptide-major histocompatibility complex (pMHC) interactions play a vital role in initiating immune responses against pathogens, and the specificity of TCRpMHC interactions is crucial for developing optimized therapeutic strategies. The advent of high-throughput immunological a...

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Detalles Bibliográficos
Autores principales: Ghoreyshi, Zahra S., George, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539903/
https://www.ncbi.nlm.nih.gov/pubmed/37781387
http://dx.doi.org/10.3389/fimmu.2023.1228873