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T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures
Immune checkpoint immunotherapies act to block inhibitory receptors on the surface of T cells and other cells of the immune system. This can increase activation of immune cells and promote tumour clearance. Whilst this is very effective in some types of cancer, significant proportions of patients do...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539945/ https://www.ncbi.nlm.nih.gov/pubmed/37386922 http://dx.doi.org/10.1042/EBC20220247 |