Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability

Glutathione (GSH) depletion, and impaired redox homeostasis have been observed in experimental animal models and patients with epilepsy. Pleiotropic strategies that elevate GSH levels via transcriptional regulation have been shown to significantly decrease oxidative stress and seizure frequency, inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sri Hari, Ashwini, Banerji, Rajeswari, Liang, Li-Ping, Fulton, Ruth E., Huynh, Christopher Quoc, Fabisiak, Timothy, McElroy, Pallavi Bhuyan, Roede, James R., Patel, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539966/
https://www.ncbi.nlm.nih.gov/pubmed/37769522
http://dx.doi.org/10.1016/j.redox.2023.102895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539966/
https://www.ncbi.nlm.nih.gov/pubmed/37769522
http://dx.doi.org/10.1016/j.redox.2023.102895

Ejemplares similares