Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer

Our previous clinical trial (Identifier: NCT02605265) revealed that addition of irinotecan (IRIN) to neoadjuvant chemoradiotherapy for rectal cancer could improve the curative effect. However, the adverse effects caused by IRIN limited the wide application of IRIN chemoradiotherapy. This study aimed...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Zhang, Tianyu, Zheng, Yile, Li, Yuting, Tang, Xiyuan, Chen, Qianping, Mao, Wei, Li, Weiwei, Liu, Xiangsheng, Zhu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540048/
https://www.ncbi.nlm.nih.gov/pubmed/37779919
http://dx.doi.org/10.1016/j.mtbio.2023.100809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540048/
https://www.ncbi.nlm.nih.gov/pubmed/37779919
http://dx.doi.org/10.1016/j.mtbio.2023.100809

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