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De novo dedifferentiated SDH-deficient gastrointestinal stromal tumor with MDM2 amplification: case report and literature review

The dedifferentiation of the gastrointestinal stromal tumors (GISTs) has been reported in a small number of cases, usually under the pressure of the tyrosine kinase inhibitor (TKI) treatment. Herein, we described a de novo dedifferentiated GIST with the SDH deficiency in a 32-year-old Chinese woman....

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Detalles Bibliográficos
Autores principales: Gong, Qi-Xing, Ding, Ying, Zhang, Wei-Ming, Zhang, Jia-Wen, Zhang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540086/
https://www.ncbi.nlm.nih.gov/pubmed/37781202
http://dx.doi.org/10.3389/fonc.2023.1233561