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Activity Guided Azide-methyllysine Photo-trapping for Substrate Profiling of Lysine Demethylases

[Image: see text] Reversible post-translational modifications (PTMs) are key to establishing protein–protein and protein–nucleic acid interactions that govern a majority of the signaling pathways in cells. Sequence-specific PTMs are catalyzed by transferases, and their removal is carried out by a cl...

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Detalles Bibliográficos
Autores principales: Kuwik, Jordan, Hinkelman, Kathryn, Waldman, Megan, Stepler, Kaitlyn E., Wagner, Shana, Arora, Simran, Chernenkoff, Sasha, Cabalteja, Chino, Sidoli, Simone, Robinson, Renã AS, Islam, Kabirul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540216/
https://www.ncbi.nlm.nih.gov/pubmed/37703462
http://dx.doi.org/10.1021/jacs.3c07299