Cargando…
Activity Guided Azide-methyllysine Photo-trapping for Substrate Profiling of Lysine Demethylases
[Image: see text] Reversible post-translational modifications (PTMs) are key to establishing protein–protein and protein–nucleic acid interactions that govern a majority of the signaling pathways in cells. Sequence-specific PTMs are catalyzed by transferases, and their removal is carried out by a cl...
Autores principales: | Kuwik, Jordan, Hinkelman, Kathryn, Waldman, Megan, Stepler, Kaitlyn E., Wagner, Shana, Arora, Simran, Chernenkoff, Sasha, Cabalteja, Chino, Sidoli, Simone, Robinson, Renã AS, Islam, Kabirul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540216/ https://www.ncbi.nlm.nih.gov/pubmed/37703462 http://dx.doi.org/10.1021/jacs.3c07299 |
Ejemplares similares
-
Hydrophobic cavity-directed azide-acetyllysine photochemistry for profiling non-histone interacting partners of bromodomain protein 1
por: Kuwik, Jordan, et al.
Publicado: (2022) -
Deciphering and engineering chromodomain-methyllysine peptide recognition
por: Hard, Ryan, et al.
Publicado: (2018) -
Investigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases
por: Bhushan, Bhaskar, et al.
Publicado: (2018) -
Poly(glycidyl azide) as Photo-Crosslinker for Polymers
por: Zhou, Xinyan, et al.
Publicado: (2022) -
Chemical Biology of Lysine Demethylases
por: Heightman, Tom D
Publicado: (2011)