Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases

[Image: see text] Post-translational modifications with ubiquitin (Ub) and ubiquitin-like proteins (Ubls) are regulated by isopeptidases termed deubiquitinases (DUBs) and Ubl proteases. Here, we describe a mild chemical method for the preparation of fluorescence polarization substrates for these enz...

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Detalles Bibliográficos
Autores principales: Zhao, Zhou, O’Dea, Rachel, Wendrich, Kim, Kazi, Nafizul, Gersch, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540217/
https://www.ncbi.nlm.nih.gov/pubmed/37712884
http://dx.doi.org/10.1021/jacs.3c04062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540217/
https://www.ncbi.nlm.nih.gov/pubmed/37712884
http://dx.doi.org/10.1021/jacs.3c04062

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