Prevention by the CXCR2 antagonist SCH527123 of the calcification of porcine heart valve cusps implanted subcutaneously in rats

INTRODUCTION: Calcification is a main cause of bioprosthetic heart valves failure. It may be promoted by the inflammation developed in the glutaraldehyde (GA)-fixed cusps of the bioprosthesis. We tested the hypothesis that antagonizing the C-X-C chemokines receptor 2 (CXCR2) may prevent the calcific...

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Detalles Bibliográficos
Autores principales: Chabry, Yuthiline, Dhayni, Kawthar, Kamel, Saïd, Caus, Thierry, Bennis, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540224/
https://www.ncbi.nlm.nih.gov/pubmed/37781314
http://dx.doi.org/10.3389/fcvm.2023.1227589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540224/
https://www.ncbi.nlm.nih.gov/pubmed/37781314
http://dx.doi.org/10.3389/fcvm.2023.1227589

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