High CD8(+)tumor-infiltrating lymphocytes indicate severe exhaustion and poor prognosis in angioimmunoblastic T-cell lymphoma

BACKGROUND: Exhaustion of CD8(+) tumor-infiltrating lymphocytes (TILs), characterized by the overexpression of immune checkpoints (IC), is a major impediment to anti-tumor immunity. However, the exhaustion status of CD8(+)TILs in angioimmunoblastic T cell lymphoma (AITL) remains unclear. Therefore,...

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Detalles Bibliográficos
Autores principales: Zhu, Qiqi, Yang, Yiming, Deng, Xueqin, Chao, Ningning, Chen, Zihang, Ye, Yunxia, Zhang, Wenyan, Liu, Weiping, Zhao, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540231/
https://www.ncbi.nlm.nih.gov/pubmed/37781365
http://dx.doi.org/10.3389/fimmu.2023.1228004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540231/
https://www.ncbi.nlm.nih.gov/pubmed/37781365
http://dx.doi.org/10.3389/fimmu.2023.1228004

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