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High CD8(+)tumor-infiltrating lymphocytes indicate severe exhaustion and poor prognosis in angioimmunoblastic T-cell lymphoma
BACKGROUND: Exhaustion of CD8(+) tumor-infiltrating lymphocytes (TILs), characterized by the overexpression of immune checkpoints (IC), is a major impediment to anti-tumor immunity. However, the exhaustion status of CD8(+)TILs in angioimmunoblastic T cell lymphoma (AITL) remains unclear. Therefore,...
Autores principales: | Zhu, Qiqi, Yang, Yiming, Deng, Xueqin, Chao, Ningning, Chen, Zihang, Ye, Yunxia, Zhang, Wenyan, Liu, Weiping, Zhao, Sha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540231/ https://www.ncbi.nlm.nih.gov/pubmed/37781365 http://dx.doi.org/10.3389/fimmu.2023.1228004 |
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