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Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells

[Image: see text] Molecular vaccines comprising antigen peptides and inflammatory cues make up a class of therapeutics that promote immunity against cancer and pathogenic diseases but often exhibit limited efficacy. Here, we engineered an antigen peptide delivery system to enhance vaccine efficacy b...

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Detalles Bibliográficos
Autores principales: Truex, Nicholas L., Rondon, Aurélie, Rössler, Simon L., Hanna, Cameron C., Cho, Yehlin, Wang, Bin-You, Backlund, Coralie M., Lutz, Emi A., Irvine, Darrell J., Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540291/
https://www.ncbi.nlm.nih.gov/pubmed/37780364
http://dx.doi.org/10.1021/acscentsci.3c00625