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Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells
[Image: see text] Molecular vaccines comprising antigen peptides and inflammatory cues make up a class of therapeutics that promote immunity against cancer and pathogenic diseases but often exhibit limited efficacy. Here, we engineered an antigen peptide delivery system to enhance vaccine efficacy b...
Autores principales: | Truex, Nicholas L., Rondon, Aurélie, Rössler, Simon L., Hanna, Cameron C., Cho, Yehlin, Wang, Bin-You, Backlund, Coralie M., Lutz, Emi A., Irvine, Darrell J., Pentelute, Bradley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540291/ https://www.ncbi.nlm.nih.gov/pubmed/37780364 http://dx.doi.org/10.1021/acscentsci.3c00625 |
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