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Single-Nucleotide Resolution Mapping of N(6)-Methyladenine in Genomic DNA

[Image: see text] N(6)-Methyladenine (6mA) is a naturally occurring DNA modification in both prokaryotes and eukaryotes. Herein, we developed a deaminase-mediated sequencing (DM-seq) method for genome-wide mapping of 6mA at single-nucleotide resolution. The method capitalizes on the selective deamin...

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Detalles Bibliográficos
Autores principales: Ma, Cheng-Jie, Li, Gaojie, Shao, Wen-Xuan, Min, Yi-Hao, Wang, Ping, Ding, Jiang-Hui, Xie, Neng-Bin, Wang, Min, Tang, Feng, Feng, Yu-Qi, Ci, Weimin, Wang, Yinsheng, Yuan, Bi-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540296/
https://www.ncbi.nlm.nih.gov/pubmed/37780356
http://dx.doi.org/10.1021/acscentsci.3c00481