Mechanical stretch promotes apoptosis and impedes ciliogenesis of primary human airway basal stem cells

BACKGROUND: Airway basal stem cells (ABSCs) have self-renewal and differentiation abilities. Although an abnormal mechanical environment related to chronic airway disease (CAD) can cause ABSC dysfunction, it remains unclear how mechanical stretch regulates the behavior and structure of ABSCs. Here,...

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Detalles Bibliográficos
Autores principales: Lin, Li-Qin, Zeng, Hai-Kang, Luo, Yu-Long, Chen, Di-Fei, Ma, Xiao-Qian, Chen, Huan-Jie, Song, Xin-Yu, Wu, Hong-Kai, Li, Shi-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540374/
https://www.ncbi.nlm.nih.gov/pubmed/37773064
http://dx.doi.org/10.1186/s12931-023-02528-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540374/
https://www.ncbi.nlm.nih.gov/pubmed/37773064
http://dx.doi.org/10.1186/s12931-023-02528-w

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