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Neuronal MHC-I complex is destabilized by amyloid-β and its implications in Alzheimer’s disease

BACKGROUNDS: The expression of major histocompatibility complex I (MHC-I) in neurons has recently been shown to regulate neurite outgrowth and synaptic plasticity. However, its contribution to neurodegenerative diseases such as Alzheimer's disease (AD) remains largely unknown. METHODS: In this...

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Detalles Bibliográficos
Autores principales: Kim, Min-Seok, Cho, Kwangmin, Cho, Mi-Hyang, Kim, Na-Young, Kim, Kyunggon, Kim, Dong-Hou, Yoon, Seung-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540404/
https://www.ncbi.nlm.nih.gov/pubmed/37773139
http://dx.doi.org/10.1186/s13578-023-01132-1