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Neuronal MHC-I complex is destabilized by amyloid-β and its implications in Alzheimer’s disease
BACKGROUNDS: The expression of major histocompatibility complex I (MHC-I) in neurons has recently been shown to regulate neurite outgrowth and synaptic plasticity. However, its contribution to neurodegenerative diseases such as Alzheimer's disease (AD) remains largely unknown. METHODS: In this...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540404/ https://www.ncbi.nlm.nih.gov/pubmed/37773139 http://dx.doi.org/10.1186/s13578-023-01132-1 |