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Lung immune signatures define two groups of end-stage IPF patients

BACKGROUND: The role of the immune system in the pathobiology of Idiopathic Pulmonary Fibrosis (IPF) is controversial. METHODS: To investigate it, we calculated immune signatures with Gene Set Variation Analysis (GSVA) and applied them to the lung transcriptome followed by unbiased cluster analysis...

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Detalles Bibliográficos
Autores principales: Cruz, Tamara, Mendoza, Núria, Casas-Recasens, Sandra, Noell, Guillaume, Hernandez-Gonzalez, Fernanda, Frino-Garcia, Alejandro, Alsina-Restoy, Xavi, Molina, María, Rojas, Mauricio, Agustí, Alvar, Sellares, Jacobo, Faner, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540496/
https://www.ncbi.nlm.nih.gov/pubmed/37770891
http://dx.doi.org/10.1186/s12931-023-02546-8