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Dose Dependent Effect of Sulfamethoxazole on Inhibiting K(ATP) Channel of Mouse Pancreatic β Cell

Sulfamethoxazole (SMX) is widely used as an antibiotic in the clinical application with side effects of hypoglycemia. This is because SMX contains the sulfonamide structure, which closes ATP-sensitive potassium (K(ATP)) channels and induces insulin secretion. However, there are no detail reports tha...

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Detalles Bibliográficos
Autores principales: Ogata, Hiroshi, Kitamura, Shigeki, Fujiwara, Makoto, Shimizu, Masaru, Tan, Chengbo, Zhao, Songji, Maejima, Yuko, Shimomura, Kenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540586/
https://www.ncbi.nlm.nih.gov/pubmed/37780606
http://dx.doi.org/10.1177/15593258231203611