Cargando…
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K(ATP) Channel of Mouse Pancreatic β Cell
Sulfamethoxazole (SMX) is widely used as an antibiotic in the clinical application with side effects of hypoglycemia. This is because SMX contains the sulfonamide structure, which closes ATP-sensitive potassium (K(ATP)) channels and induces insulin secretion. However, there are no detail reports tha...
Autores principales: | Ogata, Hiroshi, Kitamura, Shigeki, Fujiwara, Makoto, Shimizu, Masaru, Tan, Chengbo, Zhao, Songji, Maejima, Yuko, Shimomura, Kenju |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540586/ https://www.ncbi.nlm.nih.gov/pubmed/37780606 http://dx.doi.org/10.1177/15593258231203611 |
Ejemplares similares
-
K(ATP) Channel Mutations and Neonatal Diabetes
por: Shimomura, Kenju, et al.
Publicado: (2017) -
Structure based analysis of K(ATP) channel with a DEND syndrome mutation in murine skeletal muscle
por: Horita, Shoichiro, et al.
Publicado: (2021) -
Memantine has no effect on K(ATP) channels in pancreatic β cells
por: Imai, Ryota, et al.
Publicado: (2018) -
Efficacy of SGLT2 inhibitors as additional treatment in Japanese type 2 diabetic patients: second or third choice?
por: Fujiwara, Makoto, et al.
Publicado: (2022) -
Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion
por: Kitamura, Shigeki, et al.
Publicado: (2023)