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The IL-25/ILC2 axis promotes lung cancer with a concomitant accumulation of immune-suppressive cells in tumors in humans and mice

BACKGROUND: Group 2 innate lymphoid cells (ILC2) can be activated by interleukin (IL)-33 or IL-25. IL-25-activated ILC2 cells help protect the host against helminth infection while exacerbating allergic-like inflammation and tissue damage in the lung. In the context of cancer, IL-33-activated ILC2 c...

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Detalles Bibliográficos
Autores principales: Bahhar, Ilham, Eş, Zeynep, Köse, Oğuzhan, Turna, Akif, Günlüoğlu, Mehmet Zeki, Çakır, Aslı, Duralı, Deniz, Magnusson, Fay C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540623/
https://www.ncbi.nlm.nih.gov/pubmed/37781372
http://dx.doi.org/10.3389/fimmu.2023.1244437