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The IL-25/ILC2 axis promotes lung cancer with a concomitant accumulation of immune-suppressive cells in tumors in humans and mice
BACKGROUND: Group 2 innate lymphoid cells (ILC2) can be activated by interleukin (IL)-33 or IL-25. IL-25-activated ILC2 cells help protect the host against helminth infection while exacerbating allergic-like inflammation and tissue damage in the lung. In the context of cancer, IL-33-activated ILC2 c...
Autores principales: | Bahhar, Ilham, Eş, Zeynep, Köse, Oğuzhan, Turna, Akif, Günlüoğlu, Mehmet Zeki, Çakır, Aslı, Duralı, Deniz, Magnusson, Fay C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540623/ https://www.ncbi.nlm.nih.gov/pubmed/37781372 http://dx.doi.org/10.3389/fimmu.2023.1244437 |
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