Current approaches and potential challenges in the delivery of gene editing cargos into hematopoietic stem and progenitor cells

Advancements in gene delivery and editing have expanded the applications of autologous hematopoietic stem and progenitor cells (HSPCs) for the treatment of monogenic and acquired diseases. The gene editing toolbox is growing, and the ability to achieve gene editing with mRNA or protein delivered int...

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Detalles Bibliográficos
Autores principales: Murugesan, Ramya, Karuppusamy, Karthik V., Marepally, Srujan, Thangavel, Saravanabhavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540692/
https://www.ncbi.nlm.nih.gov/pubmed/37780116
http://dx.doi.org/10.3389/fgeed.2023.1148693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540692/
https://www.ncbi.nlm.nih.gov/pubmed/37780116
http://dx.doi.org/10.3389/fgeed.2023.1148693

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