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Current approaches and potential challenges in the delivery of gene editing cargos into hematopoietic stem and progenitor cells
Advancements in gene delivery and editing have expanded the applications of autologous hematopoietic stem and progenitor cells (HSPCs) for the treatment of monogenic and acquired diseases. The gene editing toolbox is growing, and the ability to achieve gene editing with mRNA or protein delivered int...
Autores principales: | Murugesan, Ramya, Karuppusamy, Karthik V., Marepally, Srujan, Thangavel, Saravanabhavan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540692/ https://www.ncbi.nlm.nih.gov/pubmed/37780116 http://dx.doi.org/10.3389/fgeed.2023.1148693 |
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