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ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination

BACKGROUND: Medulloblastoma is the most common malignant pediatric brain tumor, and leptomeningeal dissemination (LMD) of medulloblastoma both portends a poorer prognosis at diagnosis and is incurable at recurrence. The biological mechanisms underlying LMD are unclear. The Abelson (ABL) tyrosine kin...

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Detalles Bibliográficos
Autores principales: Jones, Jill K, Zhang, Hengshan, Lyne, Anne-Marie, Cavalli, Florence M G, Hassen, Wafa E, Stevenson, Kevin, Kornahrens, Reb, Yang, Yuanfan, Li, Sean, Dell, Samuel, Reitman, Zachary J, Herndon, James E, Hoj, Jacob, Pendergast, Ann Marie, Thompson, Eric M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540884/
https://www.ncbi.nlm.nih.gov/pubmed/37781087
http://dx.doi.org/10.1093/noajnl/vdad095