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Epigenetic dynamics during capacitation of naïve human pluripotent stem cells

Human pluripotent stem cells (hPSCs) are of fundamental relevance in regenerative medicine. Naïve hPSCs hold promise to overcome some of the limitations of conventional (primed) hPSCs, including recurrent epigenetic anomalies. Naïve-to-primed transition (capacitation) follows transcriptional dynamic...

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Detalles Bibliográficos
Autores principales: Agostinho de Sousa, João, Wong, Chee-Wai, Dunkel, Ilona, Owens, Thomas, Voigt, Philipp, Hodgson, Adam, Baker, Duncan, Schulz, Edda G., Reik, Wolf, Smith, Austin, Rostovskaya, Maria, von Meyenn, Ferdinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541016/
https://www.ncbi.nlm.nih.gov/pubmed/37774033
http://dx.doi.org/10.1126/sciadv.adg1936