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Epigenetic dynamics during capacitation of naïve human pluripotent stem cells
Human pluripotent stem cells (hPSCs) are of fundamental relevance in regenerative medicine. Naïve hPSCs hold promise to overcome some of the limitations of conventional (primed) hPSCs, including recurrent epigenetic anomalies. Naïve-to-primed transition (capacitation) follows transcriptional dynamic...
Autores principales: | Agostinho de Sousa, João, Wong, Chee-Wai, Dunkel, Ilona, Owens, Thomas, Voigt, Philipp, Hodgson, Adam, Baker, Duncan, Schulz, Edda G., Reik, Wolf, Smith, Austin, Rostovskaya, Maria, von Meyenn, Ferdinand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541016/ https://www.ncbi.nlm.nih.gov/pubmed/37774033 http://dx.doi.org/10.1126/sciadv.adg1936 |
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