Cargando…

Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine

Substance use disorders (SUDs) induce widespread molecular dysregulation in the nucleus accumbens (NAc), a brain region pivotal for coordinating motivation and reward. These molecular changes are thought to support lasting neural and behavioral disturbances that promote drug-seeking in addiction. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Browne, Caleb J, Mews, Philipp, Zhou, Xianxiao, Holt, Leanne M, Estill, Molly, Futamura, Rita, Schaefer, Anne, Kenny, Paul J, Hurd, Yasmin L, Shen, Li, Zhang, Bin, Nestler, Eric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541108/
https://www.ncbi.nlm.nih.gov/pubmed/37781621
http://dx.doi.org/10.1101/2023.09.19.558477