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Probing Molecular Diversity and Ultrastructure of Brain Cells with Fluorescent Aptamers

Detergent-free immunolabeling has been proven feasible for correlated light and electron microscopy, but its application is restricted by the availability of suitable affinity reagents. Here we introduce CAptVE, a method using slow off-rate modified aptamers for cell fluorescence labeling on ultrast...

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Detalles Bibliográficos
Autores principales: Lu, Xiaotang, Wu, Yuelong, Li, Peter H., Fang, Tao, Schalek, Richard L., Su, Yaxin, Carter, Jeffery D., Gupta, Shashi, Jain, Viren, Janjic, Nebojsa, Lichtman, Jeff W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541122/
https://www.ncbi.nlm.nih.gov/pubmed/37781608
http://dx.doi.org/10.1101/2023.09.18.558240