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Systematic Perturbation of Thousands of Retroviral LTRs in Mouse Embryos
In mammals, many retrotransposons are de-repressed during zygotic genome activation (ZGA). However, their functions in early development remain elusive largely due to the challenge to simultaneously manipulate thousands of retrotransposon insertions in embryos. Here, we employed epigenome editing to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541133/ https://www.ncbi.nlm.nih.gov/pubmed/37781606 http://dx.doi.org/10.1101/2023.09.19.558531 |