Discovering chromatin dysregulation induced by protein-coding perturbations at scale

Although population-scale databases have expanded to millions of protein-coding variants, insight into variant mechanisms has not kept pace. We present PROD-ATAC, a high-throughput method for discovering the effects of protein-coding variants on chromatin. A pooled library of variants is expressed i...

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Detalles Bibliográficos
Autores principales: Frenkel, Max, Hujoel, Margaux L.A., Morris, Zachary, Raman, Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541138/
https://www.ncbi.nlm.nih.gov/pubmed/37781603
http://dx.doi.org/10.1101/2023.09.20.555752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541138/
https://www.ncbi.nlm.nih.gov/pubmed/37781603
http://dx.doi.org/10.1101/2023.09.20.555752

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