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Pathological beige remodeling induced by cancer cachexia depends on the disease severity and involves mainly the trans-differentiation of mature white adipocytes

In cancer associated cachexia (CAC), white adipose tissue undergoes morphofunctional and inflammatory changes that lead to tissue dysfunction and remodeling. In addition to metabolic changes in white adipose tissues (WAT), adipose tissue atrophy has been implicated in several clinical complications...

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Detalles Bibliográficos
Autores principales: Santos, Kaltinaitis B N H, Knobl, Pamela, Henriques, Felipe, Lopes, Magno A., Franco, Felipe O., Bueno, Luana L., Farmer, Stephen R., Batista, Miguel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541144/
https://www.ncbi.nlm.nih.gov/pubmed/37781595
http://dx.doi.org/10.1101/2023.09.18.558327