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Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

The amyloid beta (Aβ) plaques found in Alzheimer’s disease (AD) patients’ brains contain collagens and are embedded extracellularly. Several collagens have been proposed to influence Aβ aggregate formation, yet their role in clearance is unknown. To investigate the potential role of collagens in for...

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Detalles Bibliográficos
Autores principales: Jongsma, Elisabeth, Goyala, Anita, Mateos, José Maria, Ewald, Collin Yvès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541181/
https://www.ncbi.nlm.nih.gov/pubmed/37728486
http://dx.doi.org/10.7554/eLife.83465