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FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m(6)A methylation of TNIP1

Endothelial dysfunction is a critical and initiating factor of the vascular complications of diabetes. Inflammation plays an important role in endothelial dysfunction regulated by epigenetic modifications. N6-methyladenosine (m(6)A) is one of the most prevalent epigenetic modifications in eukaryotic...

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Detalles Bibliográficos
Autores principales: Zhou, Chuandi, She, Xinping, Gu, Chufeng, Hu, Yanan, Ma, Mingming, Qiu, Qinghua, Sun, Tao, Xu, Xun, Chen, Haibing, Zheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541204/
https://www.ncbi.nlm.nih.gov/pubmed/37781923
http://dx.doi.org/10.1172/JCI160517