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FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m(6)A methylation of TNIP1
Endothelial dysfunction is a critical and initiating factor of the vascular complications of diabetes. Inflammation plays an important role in endothelial dysfunction regulated by epigenetic modifications. N6-methyladenosine (m(6)A) is one of the most prevalent epigenetic modifications in eukaryotic...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541204/ https://www.ncbi.nlm.nih.gov/pubmed/37781923 http://dx.doi.org/10.1172/JCI160517 |